Lauren and Katie, college frenemies with a mutual good friend, move in together at age 28 in order to afford an amazing Gramercy Park apartment. The unlikely pair start a phone sex line and become best friends while learning about this hilarious world of vibrators, fake orgasms and nighttime callers. When the hot line is hung up and reality comes calling, the most meaningful relationship of their lives is put to the test.

In high school, Matt and Ryan were best friends. More than friends, actually. But in the ensuing ten years, they've lost contact. So when Matt receives an invitation to Ryan's wedding he's surprised - especially that Ryan is marrying a woman! Matt interrupts his ideal alternative lifestyle to return to his hometown. He plans to rescue his former love from whatever "she-devil" has trapped him into this huge mistake. On the other hand, Ryan's perky fiancé Alex takes quite the liking to Matt. Is she very cunning, disarmingly ditsy, completely adorable - or all three? As Matt tries to rekindle the old flame, Ryan is intent on putting out any sparks. Ryan dismisses their old romance as just a high school thing, but Matt realizes Ryan may still be the love of his life. All the while, Matt must deal with "his new best friend" Alex, the two families, and a hometown he thought he'd left entirely in the past...